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Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | 47 € | In Stock | |
25 mg | 76 € | In Stock | |
50 mg | 92 € | In Stock | |
100 mg | 170 € | In Stock | |
200 mg | 255 € | In Stock | |
1 mL x 10 mM (in DMSO) | 47 € | In Stock |
Description | Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval. |
Alias | U70226E, Corvert Fumarate |
Molecular Weight | 885.23 |
Formula | (C20H36N2O3S)2·C4H4O4 |
Cas No. | 122647-32-9 |
Smiles | OC(=O)\C=C\C(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | H2O: 50 mg/ml (56.48 mM), Sonication is recommended DMSO: 50 mg/ml (56.48 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
H2O/DMSO
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